ORCHARD PARK, N.Y. -- Guard Richie Incognito knew LeSean McCoys right knee was fine when the Bills running back was already gabbing in Buffalos locker room during halftime.As long as Shadys talking, hes fine, Incognito said.If knocking knees with 49ers linebacker Nick Bellore late in the first half couldnt slow down the player nicknamed, Shady, what chance did the 49ers porous run defense have?McCoy had 140 yards rushing and matched a career high by scoring three times, and the Bills extended their winning streak to four with a 45-16 victory over San Francisco and new starter Colin Kaepernick Sunday.Buffalo fans greeted Kaepernick roughly for his leadership among athletes protesting during the national anthem. They booed him loudly, sold anti-Kaepernick T-shirts and roughed up a dummy wearing his jersey.Kaepernick finished 13 of 29 for 187 yards, including a 53-yard touchdown pass to Torrey Smith. But San Francisco (1-5) couldnt finish drives, settling for three field goals by Phil Dawson, in losing its fifth straight game.I thought he was OK, coach Chip Kelly said of Kaepernick, whom he promoted over Blaine Gabbert following a 33-21 loss to Arizona. But overall, offensively as a group, we need to run the ball better and we need to be better at the passing game.Kelly wouldnt commit to who will start next week against Tampa Bay.Yeah, well see, he said.Tyrod Taylor threw two touchdown passes in helping Buffalo win four straight for the first time since the start of the 2008 season.The 49ers allowed 312 yards rushing -- Buffalos best outing since 1992. The defense has allowed 981 yards on the ground in its past five games.The Bills blew the game open by scoring 21 points over a span of 7:02 straddling the third and fourth quarters.Taylor completed a 30-yard pass to Justin Hunter . Then the 49ers were stopped for no gain on a fourth-and-1 at Buffalos 40.After McCoy put the Bills up 31-16 with 10:53 left in the fourth quarter, the Bills got the ball back on after Keshawn Martin fumbled the kickoff.Two plays later, Taylor hit Robert Woods for a 5-yard touchdown pass.McCoy scored twice on 18-yard runs and another on a 4-yard scamper in his second meeting against Kelly. McCoy expressed bitter feelings toward Kelly for trading him from Philadelphia to Buffalo.To sit here and tell you that it didnt affect me last year, I would be lying, McCoy said. But Im past that. Its a whole year later.HAT-TRICKMcCoys 3-TD game was the third of his career, and first since Philadelphias 45-19 win over the Rex Ryan-coached Jets in 2011. He became Buffalos first player to score three times rushing since Willis McGahee had four TDs against Seattle in 2004.Backup Mike Gillislee closed out the scoring with a 44-yard run. Buffalos 45 points were the most since a 49-31 win at Cincinnati in 2010.RYANS DBills LB Lorenzo Alexander extended his sack streak to six games, matching the teams longest since Aaron Schobel did it during the 2006 season. The 10-year journeyman now has eight sacks this year.With three sacks on Sunday, Buffalo upped its total to 20 -- one fewer than the team had all last season.KAEPERNICK PROTESTFans chanted USA! USA! USA! shortly before Kaepernick knelt for the anthem.To be honest, I was focused on football so I really wasnt listening to what was going on in the stands, Kaepernick said.Outside New Era Field, one vendor was selling T-shirts against Kaepernick.INJURIES49ers: RB Carlos Hyde (shoulder), CB Rashard Robinson (concussion protocol).Bills: TE Charles Clay (ankle), WR Kevon Seymour (shoulder) and WR Robert Woods (right foot).BLOWN COVERAGEBuffalos defensive backfield left Smith wide open in scoring on his 53-yard catch and run . Cornerback Stephon Gilmore let Smith blow past him at the line of scrimmage leaving Smith open up the right sideline. He easily caught Kaepernicks pass and then cut into the middle to avoid being tackled by safety Aaron Williams who was Buffalos only defender deep.NEXT UP:49ers: Host Tampa Bay on Oct. 23.Bills: Play at AFC East rival Miami on Oct. 23.---AP NFL website: www.pro32.ap.org and http://twitter.com/AP-NFLScarpe Nmd Scontate . Datsyuk will miss Tuesdays game against New Jersey and could be sidelined longer, while Cleary will likely miss at least the next three games. Its been an injury-plagued season for Datsyuk, who has suited up for just 39 games. Scarpe Stan Smith Ingrosso . Once again, DeLaet finished tied for second at a PGA Tour stop on the weekend, this time at the Waste Management Phoenix Open. The pride of Weyburn, Sask. http://www.scarpenmdscontate.it/scarpe-yeezy-350-outlet.html . -- Kyrie Irvings last-minute 3-pointer helped seal another victory for Cleveland -- and the Cavaliers longest winning streak since LeBron James left. Adidas Nmd Sconti . -- Nathan Pancel scored twice as the Sudbury Wolves defeated the North Bay Battalion 4-2 on Saturday in Ontario Hockey League action. Scarpe Nmd Italia . They were putting most of their energy into a record-setting offensive display.The opening tee shot of The Open will be shown live for the first time as part of Sky Sports round-the-clock coverage of golfs pre-eminent Major.Sky Sports will dedicate an entire channel to the Championship, offering 10 days of programming including live coverage of all four days play and practice rounds, evening highlights of each days play plus a host of documentaries and shows exploring the unique allure of The Open.The channel launches on July 11, when Sky Sports 1 HD becomes Sky Sports The Open. Skys live coverage of The 145th Open at Royal Troon will begin on July 14, ahead of the opening tee shot at 6.35am which will be shown live for the first time on television in the UK and Ireland. The Championship continues until July 17. Sky Sports managing director Barney Francis said: The Open is the pre-eminent golf Major and Sky Sports will offer the Championship the coverage it deserves. With all four Majors and the Ryder Cup in 2016, theres never been more golf on Sky Sports With a dedicated channel, we will offer viewers the complete story live from Royal Troon, from the opening tee shot to the final putt. Were excited and honoured to be covering the event and cant wait for it to begin.R&A chief executive Martin Slumbers said: The Open is a true celebration of world-class sport. We are delighted with the comprehensive and innovative coverage that Sky Sports will deliver from the build-up to the Championship at Royal Troon through to the crowning of the Champion Golfer of the Year. Royal Troon last hosted the Open Championship in 2004 The Open holds a special place in the hearts of sports fans who appreciate the unrelenting challenge that is presented to the worlds best players, and we know that Sky Sports will broadcast the Championship with great insight and expertise.ddddddddddddCoverage will feature commentary and analysis from some of the biggest names in golf including Paul McGinley, Butch Harmon and Colin Montgomerie. Sky Sports award-winning golf production team will utilise some of the latest broadcast technology, including virtual analysis of the course and selected player swings. Zach Johnson claimed the Claret Jug in a three-man play-off last year Skys coverage of The Open will be a highlight of another unmissable summer of sport on Sky Sports, which includes live England Test cricket against Sri Lanka and Pakistan, every Formula 1 Grand Prix, including Silverstone, and Englands rugby union tour of Australia. Then in August, there will be 126 live Premier League games, with more top picks and Friday night matches for the first time,This year, Sky Sports is the only place to watch all four Majors and the Ryder Cup. The full schedule is available to those that subscribe to Sky Sports and to non-subscribers through online streaming service NOW TV, available on 60 devices, which offers access to seven Sky Sports channels for £6.99 a day or through a week pass at £10.99. The clubhouse at Royal Troon Golf Club On the same day that Sky Sports The Open launches, Sky Sports channel numbers will change, with Sky Sports News HQ moving to Sky electronic programme guide (EPG) number 406, with Sky Sports 1 becoming 401.Sky Sports channel listings from July 11401 - Sky Sports 1 (Sky Sports The Open)402 - Sky Sports 2403 - Sky Sports 3404 - Sky Sports 4405 - Sky Sports 5406 - Sky Sports News HQ407 - Sky Sports F1Watch the Open throughout the week from July 11-17 live on Sky Sports - your home of golfAlso See:Open Championship newsAll four majors live on SkyRecap: Johnsons 2015 victoryGolf live on Sky Sports 4 ' ' '